San Francisco 49ers 24 - Arizona Cardinals 3
Monday Night Football featured and NFC West showdown, between the San Francisco 49 and Arizona Cardinals. The 49ers’ Alex Smith almost had a perfect night going 18-fo-19 for 232 yards and three touchdowns. The 49ers’ defense was able to shut down the Cardinals’ offense and hold them to just 7 yards rushing. With the win, the 49ers take a commanding two game lead in the division. (Photo by Ralph Freso/Getty Images)