The last time Alabama and USC met in the regular season was 1978, when the Crimson Tide were the AP national champions and the Trojans finished No. 1 in the UPI poll.
Florida and Michigan will open the 2017 season in the Cowboys Classic in Arlington, Texas. The prime-time game is scheduled for Saturday, Sept. 2.
The school announced Tuesday that it has sold nearly 25,000 tickets to the game against the national champions on Sept. 1 at Cowboys Stadium in Arlington.