UPDATED | May 11, 2017 7:40 PM

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FORT WORTH (CBSDFW.COM) – A major crash involving a big rig and two other vehicles led to a highway closure in the southbound lanes of I-35 and Golden Triangle in Fort Worth.

The 18-wheeler, which was carrying powdered milk, overturned and is spread across all southbound lanes.

It happened around 1:40 Thursday afternoon.

The section of highway was closed for about six hours.

Firefighters respond to a crash involving a big rig in Fort Worth. (Chopper11)

MedStar said ten people were injured. One person is in critical condition and two people are in serious condition.

Traffic was being diverted off to Keller Hicks until the highway reopened.