HOUSTON (AP) — Four-time Gold Glove first baseman Eric Hosmer overran a towering popup with two outs in the 10th inning Saturday night, allowing the ball to fall without being touched and giving the Houston Astros a bizarre 1-0 win over the San Diego Padres.

A single by Brian McCann and a steal by pinch runner Derek Fisher — ruled safe after a video review flipped the call — set up the unusual ending.

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Alex Bregman hit the pop and Hosmer, signed to a rich free agent deal by the Padres, ran in to make the play.

Alex Bregman #2 of the Houston Astros hits an infield fly ball that Eric Hosmer #30 of the San Diego Padres could not field scoring Derek Fisher #21 for the winning run in the tenth inning at Minute Maid Park on April 7, 2018 in Houston, Texas. (Photo by Bob Levey/Getty Images)

But with reliever Phil Maton and third baseman Christian Villaneuva staying out of the way, Hosmer suddenly realized he was in trouble and had no chance to catch it. The ball plopped onto the grass a few feet behind him, between the plate, mound and first base.

Fisher scored without a throw on what was scored as a single.

Derek Fisher #21 of the Houston Astros scores on an infield fly ball by Alex Bregman #2 in the tenth inning against the San Diego Padres at Minute Maid Park on April 7, 2018 in Houston, Texas. (Photo by Bob Levey/Getty Images)

Last October at the same park, Bregman lined a single that scored the pinch running Fisher from second in the 10th inning to lift the Houston over the Los Angeles Dodgers in Game 5 of the World Series.

Chris Devenski (1-0) pitched 1 1/3 innings for the win. Robbie Erlin (0-1) took the loss.

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Gerrit Cole struck out 11 in seven sharp innings for Houston, giving up five hits and walking none. Since being acquired by the champion Astros, he has given up one run in 14 innings and fanned 22, a franchise record for the most strikeouts through the first two starts.

Padres starter Bryan Mitchell worked out six walks in 5 2/3 innings, allowing three hits. The Astros loaded the bases in the fifth, but Bregman flied out to end the threat.

Alex Bregman #2 of the Houston Astros celebrates with Jake Marisnick #6 after his walk-off pop fly single in the tenth inning to beat the San Diego Padres at Minute Maid Park on April 7, 2018 in Houston, Texas. (Photo by Bob Levey/Getty Images)


Padres: Reliever Kirby Yates exited the game after throwing just one pitch in the eighth. … RHP Dinelson Lamet played catch up to 90 feet and will likely do the same again on Sunday as he continues to make progress in his recovery from elbow soreness that started in late March.
Astros: Houston activated RP James Hoyt from the disabled list and optioned him to Triple-A Fresno. … 1B Yuli Gurriel, on the disabled list after breaking his hand in February, was given an off day but will play the next three games on his rehabilitation assignment with Double-A Corpus Christi.


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Padres: Tyson Ross (1-0, 4.50 ERA) will start for San Diego in the final game of the three-game set. He earned a win in an 8-4 victory over Colorado this week.
Astros: Charlie Morton (1-0, 0.00) allowed just three hits and two walks in a strong season debut where he blanked the Orioles in six innings. He’s 5-1 with a 2.34 ERA in eight starts against San Diego.