The option, called Preferred Seats, lets a traveler reserve a seat near the front of the economy cabin for an extra fee, which starts at $4 per flight.
Fort Worth-based American says Priceline will be the first major online travel agency to sell the option, and the airline said it will offer a 25 percent discount on the fee through Sunday.
American sells the seating option on its website and reservations centers.
(© Copyright 2012 The Associated Press. All Rights Reserved. This material may not be published, broadcast, rewritten or redistributed.)