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CHARLOTTE, N.C. (AP) – Peyton Manning’s Denver Broncos will face Cam Newton’s Carolina Panthers in the 50th Super Bowl — which many expect to be the final game of Manning’s career.

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Denver (14-4) edged the New England Patriots 20-18 for the AFC title Sunday, before Carolina (17-1) ran away with a 49-15 victory over the Arizona Cardinals in the NFC.

At 39, Manning — the only five-time MVP in league history — is the oldest starting quarterback to lead a team to the Super Bowl. He is1-2 in the big game, winning with the Colts in 2007, then losing with the Colts in 2010, and losing with the Broncos in 2014.

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The Feb. 7 game at Santa Clara, California, will be the Broncos’ record-tying eighth Super Bowl, the Panthers’ second.

Carolina opened as a 4-point favorite with most bookmakers.

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